View abstract. J Ayub.Med Coll.Abbottabad. The effects of Nigella sativa on atherosclerosis and its new risk factors in hypercholesterolemic rabbits. Effectiveness of topical Nigella sativa seed oil in the treatment of cyclic mastalgia: A randomized, triple-blind, active, and placebo-controlled clinical trial. Akhtar MS, Riffat S. Field trial of Saussurea lappa roots against nematodes and Nigella sativa seeds against cestodes in children. Early research suggests that taking a specific black seed oil product twice daily for 6 weeks might reduce total cholesterol, "bad" low-density lipoprotein (LDL) cholesterol, and blood sugar levels in people with metabolic syndrome. Using black seed for culinary purposes is safe for most people. Read more: What Are the Benefits of Using Grape Seed Oil on the Face? J Med Food 2009;12(2):408-415. 2008;44:477-482. Alam MA, Nasiruddin M, Haque SF, Khan RA. Avicenna J Phytomed. Landa, P., Kokoska, L., Pribylova, M., Vanek, T., and Marsik, P. In vitro anti-inflammatory activity of carvacrol: Inhibitory effect on COX-2 catalyzed prostaglandin E(2) biosynthesis. Badary, O. Early research shows that taking black seed oil might prevent heart damage in children being treated with a drug called doxorubicin. Many people that see their facial skin to lose its brightness could be because they have digested a large portion of black seed oil. J Transl Med 2014;12:82. Phytother.Res. View abstract. A pilot study on the effects of Nigella sativa seeds aqueous extract on paediatric intractable seizures. 2016;67(6):801-817. Black seed oil side effects include allergic reactions, adverse reactions to medication and irregular contractions in pregnant women. Le, P. M., Benhaddou-Andaloussi, A., Elimadi, A., Settaf, A., Cherrah, Y., and Haddad, P. S. The petroleum ether extract of Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat. 1999;54(4):285-294. Phytomedicine 2002;9(1):69-74. A A Pract. View abstract. Infection of the throat and tonsils (tonsillopharyngitis). According to Valdez, some side effects include lowering blood pressure, lowering … LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. Plant Foods Hum.Nutr. The possible prophylactic effect of Nigella sativa seed aqueous extract on respiratory symptoms and pulmonary function tests on chemical war victims: a randomized, double-blind, placebo-controlled trial. Ilhan, A., Gurel, A., Armutcu, F., Kamisli, S., and Iraz, M. Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylenetetrazol-induced kindling in mice. J Vet.Med A Physiol Pathol.Clin Med 2001;48(10):593-599. View abstract. Protective but Non-Synergistic Effects of Nigella Sativa and Vitamin E against Cisplatin-Induced Renal Toxicity and Oxidative Stress in Wistar Rats. Am J Otolaryngol. The doctor will inform you about the possible drug interactions. The Truth About Black Seed Oil (10 Benefits and Dangers) Posted on August 20th, 2020 To say that black seed oil was the latest health food craze would be somewhat disingenuous, because in actual fact there are dozens of superfoods that could earn this label. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. The influence of Nigella sativa for asthma control: A meta-analysis. J Ethnopharmacol. View abstract. 2003;17(4):299-305. Some studies have shown that TQ, the active drug in black seed, may have a positive effect on cancer cells. However, not all research agrees. J Ethnopharmacol. However, in one study, taking 1 teaspoon (5 mL) of … Some research shows that taking black seed powder along with other medications might help to get rid of this infection. View abstract. Phytomedicine. 1-30-2009;121(3):419-424. Effect of Nigella sativa oil versus metformin on glycemic control and biochemical parameters of newly diagnosed type 2 diabetes mellitus patients. Razmpoosh E, Safi S, Abdollahi N, et al. Claudia has a PhD in Physical Activity, Nutrition and Wellness and is a Registered Dietitian. Soleymani S, Zargaran A, Farzaei MH, et al. Eczema (atopic dermatitis). View abstract. View abstract. A body mass index over 25 is considered overweight while a body mass index below 20 is considered underweight. Kooshki A, Tofighiyan T, Rastgoo N, Rakhshani MH, Miri M. Effect of Nigella sativa oil supplement on risk factors for cardiovascular diseases in patients with type 2 diabetes mellitus. Black seed is sometimes used in combination with cysteine, vitamin E, and saffron to ease the side effects of a chemotherapy drug called cisplatin. 2000;50(9):832-836. Benefits Hair. Effect of Nigella sativa (kalonji) on serum cholesterol of albino rats. View abstract. Ali, B. H. The effect of Nigella sativa oil on gentamicin nephrotoxicity in rats. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. 2003;22(1):107-113. Applying a gel containing black seed extract to the skin might help to improve acne. The study found that black seed can reduce the chances of illnesses in these organs and even improve their overall structure. Khonche A, Huseini HF, Gholamian M, Mohtashami R, Nabati F, Kianbakht S. Standardized Nigella sativa seed oil ameliorates hepatic steatosis, aminotransferase and lipid levels in non-alcoholic fatty liver disease: A randomized, double-blind and placebo-controlled clinical trial. Badar A, Kaatabi H, Bamosa A, et al. In addition to being a natural skincare aid, there are also black seed oil health benefits … The effect of thymoquinone on blood lipids in rats. Darand M, Darabi Z, Yari Z, et al. The most important product from the black seed is black seed oil, which is what is used as a natural remedy for many ailments. View abstract. The effect of thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs. Tauseef, Sultan M., Butt, M. S., and Anjum, F. M. Safety assessment of black cumin fixed and essential oil in normal Sprague Dawley rats: Serological and hematological indices. Meral, I., Yener, Z., Kahraman, T., and Mert, N. Effect of Nigella sativa on glucose concentration, lipid peroxidation, anti-oxidant defence system and liver damage in experimentally-induced diabetic rabbits. Heart damage caused by the drug doxorubicin. Effect of Nigella sativa and fenugreek on the pharmacokinetics and pharmacodynamics of amlodipine in hypertensive rats. 2005;17(2):72-74. An investigation on LD50 and subacute hepatic toxicity of Nigella sativa seed extracts in mice. View abstract. U.S. Patent 5,482,711, issued January 9, 1996. View abstract. There is a possibility that black seed oil can increase the effects of medicines that the body processes through the cytochrome p450 pathway. When taking medication – Always consult a doctor before using black seed oil. Dehkordi FR, Kamkhah AF. Nikakhlagh S, Rahim F, Aryani FH, Syahpoush A, Brougerdnya MG, Saki N. Herbal treatment of allergic rhinitis: the use of nigella sativa. Edris, A. E. Anti-cancer properties of Nigella spp. Evaluation of safety and efficacy profile of Nigella sativa oil as an add-on therapy, in addition to alpha-keto analogue of essential amino acids in patients with chronic kidney disease. 1985;35(1A):408-414. J Ethnopharmacol 1996;52:23-6. A., and Memon, R. A. Studies on the antimicrobial activity of Black seed seed (black cumin). J Ethnopharmacol. Fouda, A. M., Daba, M. H., Dahab, G. M., and Sharaf El-Din, O. View abstract. Saudi J Gastroenterol. Consider the following before taking black seed supplements: Digestive Issues Effect of Nigella sativa seed administration on prevention of febrile neutropenia during chemotherapy among children with brain tumors. Nigella sativa supplementation improves asthma control and biomarkers: a randomized, double-blind, placebo-controlled trial. Islam, S. N., Begum, P., Ahsan, T., Huque, S., and Ahsan, M. Immunosuppressive and cytotoxic properties of Nigella sativa. 7-14-2000;400(1):89-97. It should not be Aqel M, Shaheen R. Effects of the volatile oil of black seed seeds on the uterine smooth muscle of rat and guinea pig. Withdrawal from heroin, morphine, and other opioid drugs. A., Daba, M. H., Asiri, Y. We currently have no information for BLACK SEED Interactions. Epileptic Disord 2013;15:295-301. Antiinflamm Antiallergy Agents Med Chem. Effects of Nigella sativa and Lepidium sativum on View abstract. Side Effects. Phytother.Res 2009;23(9):1295-1298. Behnamfar N, Parsa Yekta Z, Mojab F, Kazem Naeini SM. For example, black seed oil for skin can be found in skin care products. View abstract. Indian J Physiol Pharmacol. View abstract. Others, however, seemed to struggle with serious gut-related side effects like vomiting, diarrhea, and subsequent dehydration. The American Botanical Council explains that black seed goes by many names, including black cumin, black seed and black caraway. View abstract. Black seed oil can be taken in a variety of ways. This survey is being conducted by the WebMD marketing sciences department. Research shows that, like most oils, you will likely experience irritation in your stomach after using black seed oil. View abstract. Complement Ther Clin Pract 2018;31:290-4. doi: 10.1016/j.ctcp.2018.03.013. Comparative evaluation of nigella sativa (Kalonji) and simvastatin for the treatment of hyperlipidemia and in the induction of hepatotoxicity. Chakravarty N. Inhibition of histamine release from mast cells by nigellone. Damage to the immune system caused by cancer drug treatment. View abstract. World J Gastroenterol. Sarac G, Kapicioglu Y, Sener S, et al. Abbas, A. T., Abdel-Aziz, M. M., Zalata, K. R., and Tel, Abd Al-Galel. Kalus, U., Pruss, A., Bystron, J., Jurecka, M., Smekalova, A., Lichius, J. J., and Kiesewetter, H. Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases. Marsik, P., Kokoska, L., Landa, P., Nepovim, A., Soudek, P., and Vanek, T. In vitro inhibitory effects of thymol and quinones of Nigella sativa seeds on cyclooxygenase-1- and -2-catalyzed prostaglandin E2 biosyntheses. 2003;88(1):63-68. Aktuelle Dermatologie 2002;28(3):74-79. View abstract. Ghannadi, A., Hajhashemi, V., and Jafarabadi, H. An investigation of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols. View abstract. Kooshki A, Forouzan R, Rakhshani MH, Mohammadi M. Effect of topical application of nigella sativa oil and oral acetaminophen on pain in elderly with knee osteoarthritis: a crossover clinical trial. Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension. Quiz: What Do You Know About Vitamin B12 Deficiency? Al Jishi, S. A. and Abuo, Hozaifa B. View abstract. Skin damage caused by radiation therapy (radiation dermatitis). Research shows that applying a gel containing black seed oil to the. View abstract. Pak.J Pharm.Sci 1989;2(1):25-28. Salem AM, Bamosa AO, Qutub HO, et al. Contact Dermatitis. View abstract. J Pak Med Assoc 1991;41:185-7. When used as a topical salve, reports of mild dermatitis by some who are sensitive to topical treatments have been noted. View abstract. View abstract. Pharmacol Res. 1996;35(7):493-497. Dehavay F, Kolivras A, Scheers C. Local and systemic adverse skin reactions following the use of herbal products believed to contain Nigella sativa seeds and oil. 2016 Nov 25;8(11):3193-97. Early research shows that applying a cream containing black seed oil to the skin for 6 months can improve skin color in some people with vitiligo. View abstract. The clinical outcome of adjuvant therapy with black seed oil on intractable paediatric seizures: a pilot study.

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